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目的 探讨Pipeline血流导向装置（PED）与支架辅助弹簧圈栓塞（SAC）治疗颅内未破裂动脉瘤的疗效与安全性。方法 收集2019年1月至2024年12月接受PED和SAC治疗的颅内未破裂动脉瘤患者的临床与随访资料，包括年龄、动脉瘤特征、治疗过程、术后并发症及随访结果等数据，对两组患者的治疗效果和安全性进行统计学分析。结果 PED组与SAC组各纳入32例患者，两组基线资料差异无统计学意义（P>0.05）。PED组和SAC组术后并发症的发生率分别为0和3.1%，差异无统计学意义（P>0.05）。PED组的手术时间更短、术后动脉瘤的复发率更低、术后支架内狭窄的发生率更高、神经功能恢复状态更好，差异均有统计学意义（P<0.05）。结论 在颅内未破裂动脉瘤的介入治疗中，与支架辅助弹簧圈栓塞术相比，PED置入术具有手术时间短、动脉瘤复发率低、术后神经功能恢复更佳的优点，但术后载瘤动脉狭窄发生率较高。
Abstract：Objective To investigate the efficacy and safety of the Pipeline embolization device(PED) versus stentassisted coiling(SAC) in the treatment of unruptured intracranial aneurysms. Methods Clinical and follow-up data of 32 patients with unruptured intracranial aneurysms who underwent PED or SAC treatment from January 2019 to December 2024 were collected, including age, aneurysm characteristics, treatment process, postoperative complications and follow-up outcomes, with no statistically significant difference in baseline data between the two groups(P>0.05). Statistical analysis was performed to compare the therapeutic efficacy and safety between the two groups. Results The incidence of postoperative complications was 0 in the PED group and 3.1% in the SAC group, showing no statistically significant difference(P>0.05). The PED group had shorter operation time, lower postoperative aneurysm recurrence rate, higher incidence of postoperative in-stent stenosis and better neurological function recovery, with all differences statistically significant(P<0.05). Conclusions In the endovascular treatment of unruptured intracranial aneurysms, compared with stent-assisted coiling, Pipeline embolization device has the advantages of shorter operation time, lower aneurysm recurrence rate and better postoperative neurological function recovery, but it is associated with a higher incidence of postoperative parent artery stenosis.
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基本信息:
中图分类号:R651.12
引用信息:
[1]倪成志,宗钢,汪宇阳,等.Pipeline血流导向装置与支架辅助弹簧圈栓塞治疗颅内未破裂动脉瘤的疗效对比：一项单中心回顾性研究[J].中华神经外科疾病研究杂志,2026,20(02):49-54.
2026-02-05
2026-02-05